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Lymphoid disorders

  • Chronic Lymphocytic Leukaemia (M94)
    Molecular investigations: TP53 sequence analysis - NGS analysis of the TP53 gene only
    FISH as outlined in the Test Directory
  • B Cell Non-Hodgkin Lymphoma (M95)
    FISH for Ig rearrangement (M95.3)
  • Burkitt Lymphoma (M96)
    FISH as outlined in the Test Directory
  • Burkitt Like Lymphoma with 11q Abnormalities (M97)
    FISH for 11q copy number (M97.1)
  • Large B Cell Like Lymphoma with IRF4 Rearrangement (M98)
    FISH for IRF4 rearrangement (M98.1)
  • High Grade Lymphoma (M99)
    FISH as outlined in the Test Directory
  • ALK Positive Large B Cell Lymphoma (M101 & M182)
    FISH for ALK rearrangement (M101.1)
  • Mantle Cell Lymphoma (M102)
    Molecular investigations: TP53 sequence analysis - NGS analysis of the TP53 gene only
    FISH for CCND1 rearrangements (M102.2)
  • Follicular Cell Lymphoma (M103)
    FISH as outlined in the Test Directory
  • Lymphoplasmacytic Lymphoma / Waldenstrom Macroglobulinaemia (M104)
    Molecular investigations: MYD88 targeted analysis - hotspot analysis using qPCR
  • IgM Monoclonal Gammopathy of Uncertain Significance (M105)
    Molecular investigations: MYD88 targeted analysis - hotspot analysis using qPCR
  • MALT Lymphoma (M107)
    FISH for MALT1 rearrangement (M107.4)
  • Hairy Cell Leukaemia (M108)
    Molecular investigations: BRAF V600E - hotspot analysis
  • T Cell Non-Hodgkin Lymphoma (M111)
    FISH for TCR rearrangements (M111.4)
  • ALK Negative Anaplastic Large Cell Lymphoma (including primary cutaneous subtypes) (M112)
    FISH for IRF4/DUSP22 rearrangement (M112.3)

Last reviewed:10 November 2023