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Clinical Immunology

Clinical Immunology provides a comprehensive service for patients with immune-mediated disease.

Our service encompasses:

  • immune deficiency
  • C1 inhibitor deficiency
  • complex allergy
  • systemic autoimmune disease
  • autoimmune neuropathies

Clinical Immunology Day Unit

Level 2, John Radcliffe Hospital (main corridor, opposite Pharmacy).

Outpatient clinics

Immunology Day Clinic

The dedicated Immunology Day Clinic consists of a treatment room and consulting rooms of various sizes.

Primary Immune Deficiency (PID) Clinic

Primary Immune Deficiency (PID) clinics run two/three days per week.

Immunoglobulin Treatment Clinic

A nurse-led Immunoglobulin Treatment Clinic runs two days per week.

Patients with antibody deficiencies receive immunoglobulin either intravenously or subcutaneously on a regular basis. Suitable patients are trained to perform their infusions at home helping them to be independent in managing their long-term condition.

Ig-responsive autoimmune disease patients who are receiving immunoglobulin following approval from the Thames Valley Immunoglobulin Assessment Panel (SIRAP) for long-term treatment, if suitable, are offered the facility to train for home therapy either intravenously or subcutaneously. All these patients are reviewed medically at regular intervals.

Other training covered in the department is the treatment of C1 esterase inhibitor patients. Patients are carefully selected and attend for a training period to learn how to self-administer Icatibant, Lanadelumab or C1 esterase inhibitor product.

Depending on the need of the patient, this could be as a regular maintenance dose or use for treatment of an acute attack. The patient's venepuncture skills are reviewed as part of regular home therapy reviews undertaken by our nurses.

Allergy Clinic Day

Dr Misbah, Dr Jain, Dr Patel and Junior Medical Team.

An Allergy Clinic Day with a Bee and Wasp Desensitisation Clinic run on Monday mornings with a Drug Allergy Clinic in the afternoons.

Drug Challenges

These are carried out as a day cases on Thursdays following clinical assessment in the Outpatient Clinic.

General Allergy Clinic

Dr Jain and Dr Patel

A General Allergy Clinic runs in the Dermatology Department, Churchill Hospital.

Children's clinics

Dr Patel

These run in a multi-specialist clinic in Oxford Children's Hospital, with a Consultant Immunologist in attendance.

A speically-trained Immunology Specialist Nurse Practitioner attends as needed.

Our team

Consultants

Dr Rashmi Jain

Consultant Immunologist
Specialty: Clinical Immunology and Allergy
Special interests: immunodeficiency, hereditary and acquired angioedema and allergy including food, aeroallergen, chronic urticaria, venom, and drug allergy, bee and wasp venom desensitisation.

Memberships
  • British Society of Allergy and Clinical Immunology (BSACI)
  • United Kingdom - Primary Immunodeficiency Network (UK-PIN)
  • European Society for Immune Deficiency (ESID)

Dr Siraj Misbah

Consultant Immunologist
Principal hospital: John Radcliffe
Specialty: Clinical Immunology and Allergy
Special interests: immunodeficiency, systemic autoimmune disease, drug allergy and therapeutic immunology

Memberships
  • British Society for Immunology (BSI)
  • British Society of Allergy and Clinical Immunology (BSACI)
  • United Kingdom - Primary Immunodeficiency Network (UK-PIN)
  • European Society for Immune Deficiency (ESID)
  • American Academy for Allergy, Asthma and Immunology (AAAAI)

Dr Smita Patel

Consultant Immunologist
Principal hospital: John Radcliffe
Specialty: Clinical Immunology and Allergy
Special interests: inborn errors of immunity, genomics and HSCT

Memberships
  • British Society of Allergy and Clinical Immunology (BSACI)
  • United Kingdom - Primary Immunodeficiency Network (UK-PIN)
  • European Society for Immune Deficiency (ESID)

Professor Cal MacLennan

Consultant Immunologist
Principal hospital: John Radcliffe
Specialty: Clinical Immunology
Special interests: immunity to infection, vaccine development and global health

Memberships
  • British Society of Allergy and Clinical Immunology (BSACI)
  • United Kingdom - Primary Immunodeficiency Network (UK-PIN)
  • British Society for Immunology (BSI)

Nursing team

Jeanette Brooks

Lead nurse in Immunology and Allergy
Principal hospital: John Radcliffe
Specialty: Clinical Immunology and Allergy
Special interests: Allergy especially Chronic Spontaneous Urticaria and angioedema

Memberships
  • Immunology and Allergy Nurses Group (IANG) Secretary
  • International Nursing Group for Immunodeficiencies (INGID)
  • British Society of Allergy and Clinical Immunology (BSACI)
  • United Kingdom - Primary Immunodeficiency Network (UK-PIN)

Rosalind Fisher

Specialist Nurse Practitioner
Principal hospital: John Radcliffe
Specialty: Clinical Immunology and Allergy
Special interests: Allergy and HAE

Memberships
  • International Nursing Group for Immunodeficiencies (INGID) Board
  • British Society of Allergy and Clinical Immunology (BSACI)
  • Immunology and Allergy Nurses Group (IANG)
  • United Kingdom - Primary Immunodeficiency Network (UK-PIN)
  • European Society for Immune Deficiency (ESID)

Karen Abrams

Specialist Nurse Practitioner
Principal hospital
: John Radcliffe
Specialty: Clinical Immunology and Allergy
Special interests: home therapy training and neurology

Memberships
  • Immunology and Allergy Nurses Group (IANG)
  • International Nursing Group for Immunodeficiencies (INGID)
  • United Kingdom - Primary Immunodeficiency Network (UK-PIN)

Holly Hurst

Specialist Nurse Practitioner
Principal hospital: John Radcliffe
Specialty: Clinical Immunology and Allergy
Special interests: HAE and psychological support

Memberships
  • Immunology and Allergy Nurses Group (IANG)
  • International Nursing Group for Immunodeficiencies (INGID)
  • United Kingdom - Primary Immunodeficiency Network (UK-PIN)

Elizabeth Davis

Paediatric Specialist Nurse Practitioner
Principal hospital: Oxford Children's Hospital
Specialty: Paediatric Immunology under the care of the Paediatric Infectious Diseases Team
Special interests: Paediatric home therapy training, HAE and Transitioning Patients from Paediatric to Adult Services

Memberships
  • Immunology and Allergy Nurses Group (IANG)
  • International Nursing Group for Immunodeficiencies (INGID)
  • United Kingdom - Primary Immunodeficiency Network (UK-PIN)

Links

Patient involvement

Find us and contact us

Clinical Immunology Department
Level 4 Academic Centre
John Radcliffe Hospital
Headley Way
Headington
Oxford OX3 9DU

How to find the John Radcliffe Hospital

Tel: 01865 743164
Monday to Thursday 9.00am - 5.00pm
Friday 9.00am - 4.30pm

Email

General enquiries: ouh-tr.ouh.immunologysecretaries@nhs.net

Nursing Team: ouh.immunologynurses@nhs.net

Appointments

If you cannot attend your clinic appointment, please call/email us in advance so we can offer the appointment to another patient.

Medical emergency out of hours

Patients

For medical assistance: call 111 / 999 or your GP practice.

Medical professionals

Out of hours, weekends / public holidays: 0300 304 7777 [Switchboard]

Ask to speak to the Consultant Immunologist on call.

Please also visit:

Clinical Immunology referrals

Last reviewed:20 June 2023