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Oxford University Hospitals NHS Foundation Trust

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Chronic myeloid leukaemia (M84)

Molecular investigations

Detection of the BCR-ABL fusion gene - screen for the presence of BCR-ABL fusion transcripts using multiplex PCR.

BCR-ABL quantification - quantification of BCR-ABL transcript level and monitoring of minimal residual disease.

BCR-ABL T315I analysis - pyrosequencing for this variant only. M84.8 and M84.9 can be undertaken as sendaway tests. Please contact us to discuss.

Karyotyping

As outlined in the Test Directory.

FISH

As outlined in the Test Directory.