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Acute lymphoblastic leukaemia (M91)

Molecular investigations

Detection of the BCR-ABL fusion gene - screen for the presence of BCR-ABL fusion transcripts using multiplex PCR.

BCR-ABL quantification - quantification of BCR-ABL transcript level and monitoring of minimal residual disease.

BCR-ABL T315I analysis - pyrosequencing for this variant only. M91.11 and M91.12 can be undertaken as sendaway tests. Please contact us to discuss.


As outlined in the Test Directory.


There are several of the rarer FISH investigations outlined in the Test Directory that we do not provide (e.g. M91.25, M91.27 & M91.29 as well as many others).

Please contact us to discuss forwarding the sample elsewhere for FISH investigations.

WGS for diagnostic samples

If there are tumour and germline samples available, along with appropriate consent, these will be forwarded to the WMRGL for further processing.

Last reviewed:02 August 2021