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Oxford University Hospitals NHS Foundation Trust

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Neuropathology and Ocular Pathology

Updated 20 April 2018

The Department of Neuropathology and Ocular Pathology is integrated into the Neurosciences, Trauma and Specialist Services of the Trust, and regional cancer networks, and has close associations with neuroscience research groups at the University of Oxford.

The department provides a CPA accredited (transitioning to UKAS accreditation to ISO 15189:2012) diagnostic pathology service for diseases affecting the nervous system, including eye and muscle, for the central Oxford and regional hospitals, including those from the private sector; it also provides a national and international referral service.

The range of services includes:

  • diagnostic histopathology of biopsies of the central and peripheral nervous system and their coverings
  • diagnostic histopathology of ophthalmic biopsies
  • diagnostic histopathology of muscle biopsies
  • diagnostic cytopathology of cerebrospinal fluid (CSF)
  • diagnostic histopathology of skin biopsies for small fibre neuropathies
  • diagnostic neuropathology post-mortem service for local and regional hospitals, including specialist neonatal and paediatric neuropathology and work for H.M. Coroner
  • a coordinating centre for prospective collection, neuropathological assessment and storage of CNS tissue for research and teaching (Oxford Brain Bank, jointly with the University of Oxford).

User Manual

The Neuropathology User Manual provides users with information about our department and the services we offer, as well as useful instructions and advice around specimen preparation and handling.

Neuropathology User Manual (pdf, 556 KB)

Private patients

The department accepts private referrals for second opinions or primary diagnostic assessment.

Find us and contact us

Teaching and research

As the department is part of a busy university hospital and the sole provider of specialist neuropathology and ophthalmic pathology services in Oxfordshire, it also serves as a regional teaching centre. This involves:

  • postgraduate specialist training in neuropathology and forensic neuropathology
  • specialist neuropathology training for biomedical scientists
  • teaching of Oxford Medical School undergraduate and postgraduate students (lectures, practical courses, higher degrees)
  • national postgraduate teaching for candidates preparing for fellowship of the Royal College of Pathologists (FRCPath)
  • national postgraduate courses in paediatric neuropathology.

The department is also conducting independent and collaborative research in the following areas of interest:

  • pathology and pathogenesis of multiple sclerosis in humans and experimental models
  • prospective clinico-pathological studies of aging and dementia (the Brains for Dementia Research (BDR) project)
  • pathology and genetics of movement disorders, particularly ataxias and motor neurone diseases
  • pathology of autism and developmental neurological diseases
  • pathology of paediatric brain injury
  • pathology and genetics of gliomas and pituitary adenomas

For more on these topics please visit: Nuffield Department of Clinical Neurosciences - Division of Clinical Neurology

Organ and tissue donation

The department runs the Oxford Brain Bank for neurological disease.

You can read our archive newsletters at the links below:

We accept brain and spinal cord tissue donations for research from healthy donors and those with neurological disease.

For general enquiries, please contact:

Charitable donations

It is possible to make a charitable donation to the work of the department. Please contact Dr Olaf Ansorge for more information about this.

Dementias and Neurodegeneration Research

Thames Valley DeNDRoN is an NHS-based research network that aims to improve the amount and quality of research in dementias (e.g. Alzheimer's disease and others), ataxia, Huntington's, Parkinson's and Motor Neurone Disease.

They offer a specialist research service within the NHS, helping to set up, run and provide research opportunities to patients, carers and clinicians. They offer a unique service, giving members of the public the opportunity to find out more about the latest research in these areas, as well as how they can get involved.

They are part of the National Institute for Health Research (NIHR).

They also run a specific study called 'Brains for Dementia Research'.

For more information please contact:

Brains for Dementia Research