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The Oxford Calcium Channel Antagonism Study – an exploration of the role L-type calcium channels in cognition and sleep

Trial categories: Brain

Sponsoring organisation: University of Oxford

Understanding the role of calcium channels in mood instability, cognitive function and sleep

Have you been experiencing problematic moods?

Have you been experiencing mood swings? Have you recently engaged in risky behaviour, been so hyper that you got into trouble, had much more energy than usual and/or been so irritable that you started fights?

We are investigating the role of calcium channels in mood instability, cognitive function and sleep in individuals (between 18 and 35 years old) who show some symptoms of mood disorders.

This study involves being randomised to either a calcium channel antagonist (medication used to treat hypertension) or placebo, playing daily app-based games presented on an iPad, filling out daily and weekly mood questionnaires, as well as completing 2 MRI (Magnetic Resonance Imaging) and MEG (Magnetoencephalography) brain scans during a 4-week period.

Participants will be reimbursed for their time and travel expenses.

To get involved, please complete our OxCaMS online questionnaire and we can send you further information.

Completing the questionnaire helps us assess your eligibility and does not obligate you to take part.

Tel: 01865 613101

Study in association with Oxford Health NHS Foundation Trust