Immunochemistry

Immunochemistry is the study of immunological proteins within different biological fluids including serum, urine and CSF. The detection of these proteins employs a range of differing techniques from electrophoresis and immunofixation to nephelometry/turbidimetry.

• Guide to Referral of Paraproteins to Secondary Care
• Haematology website

The assays available within the Clinical Immunology Laboratory include:

• Acute Phase Proteins (Alpha-1-antitrypsin, Caerulolasmin and Complement)
• Alpha-1-antitrypsin phenotypes
• Beta-2 Microglobulin
• Complement Function assays
• C1 Esterase Inhibitor - Quantitative and Functional
• Cryoglobulin detection and quantification
• Functional antibodies to: Haemophilus influenzae type B, Tetanus Toxoid
• Pneumococcal polysaccharide - total levels and serotype specific levels
• Immunglobulins (IgG, IgA and IgM) and serum electrophoresis
• IgG Subclasses (IgG1, IgG2, IgG3 and IgG4)
• Oligoclonal Band detection in paired CSF and Serum samples
• Rheumatoid Factor
• Serum free light chains
• Urine Electrophoresis