Alpha-1-Antitrypsin

Also known as: AAT; α-1 proteinase inhibitor

Measurement of alpha-1 anti-trypsin (α1-AT) levels is useful in the investigation of emphysema and unexplained liver disease in adults. In paediatric practice, alpha-1 anti-trypsin deficiency is associated with neonatal jaundice. Patients with low α1-AT levels will be phenotyped to determine homo- or heterozygosity of deficiency alleles. Alpha-1anti-trypsin levels can rise as part of the acute phase response.

Specimen requirements

Serum only - 1ml

Cost

Price on application

Laboratory turnaround time

3 days

Laboratory method

Turbidimetry

Reference range/units

107 - 209mg/dl

Associated tests

Not applicable

Sample stability

2 weeks at 2-8ºC

Shipping and storage

UK and Ireland

Ambient temperature and first class post. Hays DX users please enquire via email below.

International

Ambient temperature if courier will deliver within 72 hours otherwise consider refrigerated transport. Freezing is not a requirement.

Ensure delivery Monday to Friday 09:00 - 17:30.

Further information and contact details

For further information, email immunology.office@nhs.net