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Clinical Haematology

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If you have a bleeding disorder, all vaccinations should if possible be administered subcutaneously - just under the skin, rather than deep in the muscle.

You can obtain all your vaccinations via your GP practice nurse - this includes the annual flu vaccination and all travel vaccinations.


COVID-19 vaccinations cannot be given subcutaneously and must be given in the muscle (intramuscularly).

If you are due to have a COVID-19 vaccination or booster, please contact us and we can advise.

In general, patients with factor levels of less than 0.05 IU/ml are most at risk of bleeding after intramuscular vaccination. The smallest possible fine needle should be used for the vaccination, followed by firm pressure to the site (without rubbing) for at least two minutes, and ideally five minutes.


If you need plasma-derived factor products (made from donated human blood) as part of your treatment, or if you travel abroad regularly, your doctor may recommend vaccination against Hepatitis A and B. These vaccinations should be given subcutaneously at your GP practice.

If you have already been vaccinated against Hepatitis B, your doctor may check your antibody levels (after three months from when you finished your course) to assess how well you have responded.

Most people do not get boosters against Hepatitis B unless they are healthcare workers, have kidney disease or have been exposed to Hepatitis B. Please check with your doctor if you think you fit into any of these categories.

If you have any questions about vaccinations or are due a vaccination, please contact the Haemophilia Specialist Nurses.

Tel: 01865 225308 / 225316

Ensure that you have a supply of tranexamic acid at home if required.

Last reviewed:22 April 2024