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Oxford Children's Hospital

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Research in Paediatric Critical Care (PICU and PHDU)

Our aim is to give Paediatric Critical Care patients and their families the best possible care.

We are therefore passionate about clinical research, and believe we should offer every child in critical care the opportunity to be involved in research.

Research on patients is often referred to as a 'trial' or 'study', and is a structured process leading to new information about a treatment, test or condition. This new information can be used in different ways.

Examples of positive outcomes include:

  • a new drug or therapy that treats a known condition better than a previous one
  • a new test allowing us to give more accurate information about a child's condition
  • a new device that would allow us to treat children more effectively.

The decision to take part in research is always voluntary. Your child will receive excellent care whether you decide to participate or not, and you are free to withdraw your child from any study at any time.

If you have agreed to participate in a research study, the team will check regularly that you are happy to remain in the study.

Studies taking place in Paediatric Critical Care - January 2018


The aim of the Sedation AND Weaning in Children (SANDWICH) study is to determine if a protocol-based intervention for the management of children in intensive care units can reduce the duration of invasive mechanical ventilation (IVM). The study involves co-ordinated care and greater nursing involvement in the sedation and ventilator weaning of children. It will also assess cost effectiveness compared with usual care. (Open January 8th 2018)


The NET-PACK 3 Custom Audit - PICANet evaluation of Post cardiac Arrest Care in Kids, is a re-audit of patient management after cardiac arrest in UK and Irish PICUs. NET-PACK 3 has been designed to investigate the impact and compliance with the new international guidance and research data on post-arrest care as part of our clinical audit function. (Open)


The Differences in access to Emergency Paediatric Intensive Care and care during Transport (DEPICT) study is a national study aiming to determine if differences in access to Emergency Paediatric Intensive Care and care during transport affect clinical outcomes and patient experience of critically ill children. (Opens 15 January 2018)


Ventilation and weaning practice in European PICUs. (Open)

Further information

For more information on research in Paediatric Critical Care, please read this leaflet in our patient information leaflet library:

Research in Paediatric Critical Care (pdf)

Page last updated December 2017