Also known as: NSE (Cardiac Arrest)
Specimen requirements
Sample type: Serum (gold/yellow top SST)
Collection requirements: Please inform laboratory prior to collection - specimen must be separated within four hours of collection.
Cost
Price on application
Turnaround time
Analytical method
Immunoassay: Direct / Sandwich
Analysis undertaken at these site(s)
John Radcliffe Hospital
Reference intervals
NSE > 60 mcg/L at 48- 72 hours post-ROSC indicates high probability of poor neurological outcome.
NSE should be used as a part of the multimodal neuroprognostication (European Resuscitation Council Guidelines 2021).
Notes
NSE may also be requested as a tumour marker; however this is sent away to Sheffield Immunology for analysis.
