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Shine B, James T, Adler A. In primary care, is measuring free-thyroxine plus thyroid-stimulating hormone to detect hypopituitarism cost-effective? A cost utility analysis using Markov chain models. BMJ Open. 2019;9:e029369. doi: 10.1136/bmjopen-2019-029369.

Cerdeira AS, O'Sullivan J, Ohuma EO, Harrington D, Szafranski P, Black R, Mackillop L, Impey L, Greenwood C, James T, Smith I, Papageorghiou AT, Knight M, Vatish M. Randomized Interventional Study on Prediction of Preeclampsia/Eclampsia in Women With Suspected Preeclampsia: INSPIRE. Hypertension. 2019;74:983-990.

Nicholson BD, Lee MM, Wijeratne D, James T, Shine B, Oke JL. Trends in Cancer Antigen 125 testing 2003-2014: A primary care population-based cohort study using laboratory data. Eur J Cancer Care (Engl). 2019 Jan;28(1):e12914. doi: 10.1111/ecc.12914.

Shah A, Wray K, James T, Shine B, Morovat R, Stanworth S, McKechnie S, Kirkbride R, Griffith DM, Walsh TS, Drakesmith H, Roy N. Serum hepcidin potentially identifies iron deficiency in survivors of critical illness at the time of hospital discharge. Br J Haematol. 2019 Jan;184(2):279-281. doi: 10.1111/bjh.15067.

Juszczak A, Pavić T, Vučković F, Bennett AJ, Shah N, Pape Medvidović E, Groves CJ, Šekerija M, Chandler K, Burrows C, Rojnić Putarek N, Vučić Lovrenčić M, Ćuća Knežević J, James TJ, Gloyn AL, Lauc G, McCarthy MI, Owen KR, Gornik O. Plasma Fucosylated Glycans and C-Reactive Protein as Biomarkers of HNF1A-MODY in Young Adult-Onset Nonautoimmune Diabetes. Diabetes Care. 2019 Jan;42(1):17-26.

Yang E, Chalisey A, Reschen ME, Shine B, Lasserson DS, O'Callaghan CA. Reduced kidney function at presentation in unselected acute emergency medical admissions: incidence, outcome and associated factors. Acute Med. 2019;18:158-164.

Ordóñez-Mena JM, Fanshawe TR, McCartney D, Shine B, Van den Bruel A, Lasserson D, Hayward G. C-reactive protein and neutrophil count laboratory test requests from primary care: what is the demand and would substitution by point-of-care technology be viable? J Clin Pathol. 2019 Jul;72(7):474-481.


Fairfax BP, Morgan RD, Protheroe A, Shine B, James T. Abiraterone acetate: a potential source of interference in testosterone assays. Clin Chem Lab Med. 2018 May 24;56(6):e13

Price CP, Smith I, Van den Bruel A. Improving the quality of point-of-care testing. Fam Pract. 2018 Jul 23;35(4):358-364.

Fanshawe TR, Ordóñez-Mena JM, Turner PJ, Bruel AVD, Shine B, Hayward GN. Frequencies and patterns of laboratory test requests from general practice: a service evaluation to inform point-of-care testing. J Clin Pathol. 2018 Dec;71(12):1065-1071.

Shine B, Barth JH. Big data in clinical biochemistry. Ann Clin Biochem. 2018 Sep 12:4563218800735. d

Hirst JA, Montes MDV, Taylor CJ, Ordóñez-Mena JM, Ogburn E, Sharma V, Shine B, James T, Hobbs FR. Impact of a single eGFR and eGFR-estimating equation on chronic kidney disease reclassification: a cohort study in primary care. Br J Gen Pract. 2018 Aug;68(673):e524-e530.

O'Sullivan JW, Heneghan C, Perera R, Oke J, Aronson JK, Shine B, Goldacre B. Variation in diagnostic test requests and outcomes: a preliminary metric for Sci Rep. 2018 Mar 19;8(1):4752.

Emms H, Farah G, Shine B, Boot C, Toole B, McFadden M, Lam L, Ou ZQ, Woollard G, Madhavaram H, Kyle C, Grossman AB. Falsely elevated plasma metanephrine in patients taking midodrine. Ann Clin Biochem. 2018 Jul;55(4):509-515.

Böhning D, Böhning W, Guha N, Cowan DA, Bartlett C, Sönksen PH, Holt RIG. A correction to the age-adjustment of the GH-2000 score used in the detection of growth hormone misuse. BMC Res Notes. 2018 Sep 5;11(1):650.

Sönksen PH, Holt RIG, Böhning W, Guha N, Cowan DA, Bartlett C, Böhning D. Why do endocrine profiles in elite athletes differ between sports? Clin Diabetes Endocrinol. 2018 Feb 7;4:3.

Sőnksen PH, Bavington LD, Boehning T, Cowan D, Guha N, Holt R, Karkazis K, Ferguson-Smith MA, Mircetic J, Bőhning D. Hyperandrogenism controversy in elite women's sport: an examination and critique of recent evidence. Br J Sports Med. 2018 Dec;52(23):1481-1482.

Lorenzini M, Guha N, Davison JE, Pitcher A, Pandya B, Kemp H, Lachmann R, Elliott PM, Murphy E. Isolated aortic root dilation in homocystinuria. J Inherit Metab Dis. 2018 Jan;41(1):109-115.


Sbardella E, Isidori AM, Woods CP, Argese N, Tomlinson JW, Shine B, Jafar-Mohammadi B, Grossman AB. Baseline morning cortisol level as a predictor of pituitary-adrenal reserve: a comparison across three assays. Clin Endocrinol (Oxf). 2017 Feb;86(2):177-184.

Shinkins B, Nicholson BD, Primrose J, Perera R, James T, Pugh S, Mant D. The diagnostic accuracy of a single CEA blood test in detecting colorectal cancer recurrence: Results from the FACS trial. PLoS One. 2017 Mar 10;12(3).e0171810.


Cremers S, Guha N, Shine B. Therapeutic drug monitoring in the era of precision medicine: opportunities! Br J Clin Pharmacol. 2016; 82: 900-2.

Mirzazadeh M, Morovat A, James T, Smith I, Kirby J, Shine B. Point-of-care testing of electrolytes and calcium using blood gas analysers: it is time we trusted the results. Emerg Med J 2016;33:181-6.


Perera R, McFadden E, McLellan J, Lung T, Clarke P, Pérez T, Fanshawe T, Dalton A, Farmer A, Glasziou P, Takahashi O, Stevens J, Irwig L, Hirst J, Stevens S, Leslie A, Ohde S, Deshpande G, Urayama K, Shine B, Stevens R. Optimal strategies for monitoring lipid levels in patients at risk or with cardiovascular disease: a systematic review with statistical and cost-effectiveness modelling. Health Technol Assess. 2015;19:1-401.

Mirzazadeh M, Morovat, A, James T, Smith I, Kirby J, Shine B. Point of Care Testing of electrolytes and calcium using blood gas analysers: It is time we trusted the results. (Poster W40) ACB National Meeting (Focus 2015).

Mehdi Mirzazadeh, Alireza Morovat, Tim James, Ian Smith, Justin Kirby, Brian Shine Point-of-care testing of electrolytes and calcium using blood gas analysers: it is time we trusted the results. Emerg Med J doi:10.1136/emermed-2015-204669.

Pal A, Potjer TP, Thomsen SK, Ng HJ, Barrett A, Scharfmann R, James TJ, Bishop DT, Karpe F, Godsland IF, Vasen HF, Newton-Bishop J, Pijl H, McCarthy MI, Gloyn AL. Loss-of-Function Mutations in the Cell-Cycle Control Gene CDKN2A Impact on Glucose Homeostasis in Humans. Diabetes. 2015 Nov 5. pii: db150602. [Epub ahead of print].

Nicholson BD, Shinkins B, Pathiraja I, Roberts NW, James TJ, Mallett S, Perera R, Primrose JN, Mant D. Blood CEA levels for detecting recurrent colorectal cancer. Cochrane Database Syst Rev. 2015 Dec 10;12.

Shine B, McKnight RF, Leaver L, Geddes JR. Long-term effects of lithium on renal, thyroid, and parathyroid function: a retrospective analysis of laboratory data. Lancet. 2015 Aug 1;386(9992):461-8.

Holt RI, Böhning W, Guha N, Bartlett C, Cowan DA, Giraud S, Bassett EE, Sönksen PH, Böhning D. The development of decision limits for the GH-2000 detection methodology using additional insulin-like growth factor-I and amino-terminal pro-peptide of type III collagen assays. Drug Test Anal. 2015 Sep;7(9):745-55.

Kolawole K, Herrington W, James T. Development of a UPLC Method for Metformin Quantification in Plasma (Poster) IBMS congress. Birmingham, September 2015.

Oke J, Shine B, McFadden E, Stevens R, Lasserson D, Perera R. Trends in serum creatinine testing in Oxfordshire, UK, 1993-2013: a population-based cohort study. BMJ Open. 2015 Dec 16;5(12):e009459. doi: 10.1136/bmjopen-2015-009459.


Luo X1, Xu Q, James T, Davis JJ. Redox and label-free array detection of protein markers in human serum. Anal Chem. 2014; 86 :5553-8.

Shah N, Thanabalasingham G, Owen KR, James TJ. Comparability of high-sensitivity CRP methods to detect maturity-onset diabetes of the young due to HNF1A mutations. Br J Biomed Sci. 2014; 71: 84-5.

Brian D Nicholson, Bethany Shinkins, Indika Pathiraja, Nia W Roberts,Tim J James,Susan Mallett, Rafael Perera, John N Primrose, David Mant. Blood CEA levels for detecting recurrent colorectal cancer. Protocol. Cochrane Database of Systematic Reviews. June 2014.

Shinkins B, Perera R, Nicholson B, James T, Primrose J, Mant D. CEA monitoring to detect recurrence of colorectal cancer: how should we interpret the test results? Clinical Chemistry 2014;60:1572-4.

Rehman SM, Elzain O, Mitchell J, Shine B, Bowler IC, Sayeed R, Westaby S, Ratnatunga C. Risk factors for mediastinitis following cardiac surgery: the importance of managing obesity. J Hosp Infect. 2014 Oct;88(2):96-102.

Frighi V, Morovat A, Stephenson MT, White SJ, Hammond CV, Goodwin GM. Vitamin D deficiency in patients with intellectual disabilities: prevalence, risk factors and management strategies. Br J Psychiatry. 2014 Dec;205(6):458-64.

Farmer AJ, Stevens R, Hirst J, Lung T, Oke J, Clarke P, Glasziou P, Neil A, Dunger D, M Colhoun H, Pugh C, Wong G, Perera R, Shine B. Optimal strategies for identifying kidney disease in diabetes: properties of screening tests, progression of renal dysfunction and impact of treatment - systematic review and modelling of progression and cost-effectiveness. Health Technol Assess. 2014 Feb;18(14):1-128.


Nagrebetsky A, Jin J, Stevens R, James T, Adler A, Park P, Craven A, Shine B, Farmer A. Diagnostic accuracy of urine dipstick testing in screening for microalbuminuria in type 2 diabetes: a cohort study in primary care. Family Practice. 2013;30:142-52.

Luo X, Xu M, Freeman C, James T, and Davis JJ. Ultrasensitive Label Free Electrical Detection of Insulin in Neat Blood Serum. Analytical Chemistry, 2013;85:4129-34.

Guha N. Assays for GH, IGF-I, and IGF binding protein-3. Methods Mol Biol. 2013;1065:117-28.

Patel MV, Shine BS, Watkinson P, James T. A comparison of formulae for calculating plasma osmolality in hyperosmolar hyperglycaemic state (HHS). (Poster W15) ACB National Meeting (Focus 2013).

Maunsell-Browne ZJ, Justice S, Chung K, Ferguson H, Mitchell K, Mevada C, James TJ. Iohexol Clearance: Improving Quality, Safety and Productivity for Formal Assessment of GFR. (Poster W71) ACB National Meeting (Focus 2013).

Worth C, James T, Shine B. Two year follow up audit of patients requiring CSF xanthochromia analysis. (Poster Th38) ACB National Meeting (Focus 2013).

Segal, HC, Burgess AI, Poole DL, Taj, N, James, TJ, Mehta Z, Rothwell PM. Lipoprotein associated phospholipase A2 (Lp-PLA2) and long-term prognosis after TIA and stroke. (Poster) European Stroke Conference. May 2013. London.

Morovat A, Catchpole A, Meurisse A, Carlisi A, Bekaert A, Rousselle O, Paddon M, James T, Cavalier E. IDS iSYS automated intact procollagen-1-N-terminus pro-peptide assay: Method evaluation and reference intervals in adults and children. Clin Chem Lab Med 2013; 51: 2009-18.

Rowland R, O’Hara GA, Hamilla M, Poulton I, Donaldson H, Dinsmore L, James T, Barnes E, Klenerman P, Gilbert SC, Hill A, Shine B, McShane H. Determining the validity of hospital laboratory reference intervals for healthy young adults participating in early clinical trials of candidate vaccines. Hum Vaccin Immunother. 2013; 9: 1741-51.

Shah N, Thanabalasingham G, Owen KR, James TJ. A comparison of high sensitivity CRP methods at low concentrations. (Poster) IBMS congress. Birmingham, September 2013.


Brook MO, Bottomley MJ, Mevada C, Svistunova A, Bielinska AM, James T, Kalachik A, Harden PN.
Repeat testing is essential when estimating chronic kidney disease prevalence and associated cardiovascular risk. QJM. 2012; 105: 247-255.

Watkinson PJ, Barber VS, Amira E, James T, Taylor R, Young JD. The effects of precision, haematocrit, pH and oxygen tension on point-of-care glucose measurement in critically ill patients: a prospective study. Ann Clin Biochem. 2012; 49: 144-51.

Nowak N, Szopa M, Thanabalasingham G, McDonald TJ, Colclough K, Skupien J, James TJ, Kiec-Wilk B, Kozek E, Mlynarski W, Hattersley AT, Owen KR, Malecki MT. Cystatin C is not a good candidate biomarker for HNF1A-MODY. Acta Diabetol. 2012 Feb 19. [Epub ahead of print].

Evans PD, Chung K, James TJ, Tan GD, McIntyre CW1, Dose Dependent Effect of Weight Loss on Hyperfiltration as a Result of Bariatric Surgery. British Renal Society Meeting, Manchester, May 2012.