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Oxford University Hospitals NHS Foundation Trust
Clinical Biochemistry

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Sbardella E, Isidori AM, Woods CP, Argese N, Tomlinson JW, Shine B, Jafar-Mohammadi B, Grossman AB. Baseline morning cortisol level as a predictor of pituitary-adrenal reserve: a comparison across three assays. Clin Endocrinol (Oxf). 2017 Feb;86(2):177-184.

Shinkins B, Nicholson BD, Primrose J, Perera R, James T, Pugh S, Mant D. The diagnostic accuracy of a single CEA blood test in detecting colorectal cancer recurrence: Results from the FACS trial. PLoS One. 2017 Mar 10;12(3).e0171810.


Cremers S, Guha N, Shine B. Therapeutic drug monitoring in the era of precision medicine: opportunities! Br J Clin Pharmacol. 2016; 82: 900-2.

Mirzazadeh M, Morovat A, James T, Smith I, Kirby J, Shine B. Point-of-care testing of electrolytes and calcium using blood gas analysers: it is time we trusted the results. Emerg Med J 2016;33:181-6.


Perera R, McFadden E, McLellan J, Lung T, Clarke P, Pérez T, Fanshawe T, Dalton A, Farmer A, Glasziou P, Takahashi O, Stevens J, Irwig L, Hirst J, Stevens S, Leslie A, Ohde S, Deshpande G, Urayama K, Shine B, Stevens R. Optimal strategies for monitoring lipid levels in patients at risk or with cardiovascular disease: a systematic review with statistical and cost-effectiveness modelling. Health Technol Assess. 2015;19:1-401.

Mirzazadeh M, Morovat, A, James T, Smith I, Kirby J, Shine B. Point of Care Testing of electrolytes and calcium using blood gas analysers: It is time we trusted the results. (Poster W40) ACB National Meeting (Focus 2015).

Mehdi Mirzazadeh, Alireza Morovat, Tim James, Ian Smith, Justin Kirby, Brian Shine Point-of-care testing of electrolytes and calcium using blood gas analysers: it is time we trusted the results. Emerg Med J doi:10.1136/emermed-2015-204669.

Pal A, Potjer TP, Thomsen SK, Ng HJ, Barrett A, Scharfmann R, James TJ, Bishop DT, Karpe F, Godsland IF, Vasen HF, Newton-Bishop J, Pijl H, McCarthy MI, Gloyn AL. Loss-of-Function Mutations in the Cell-Cycle Control Gene CDKN2A Impact on Glucose Homeostasis in Humans. Diabetes. 2015 Nov 5. pii: db150602. [Epub ahead of print].

Nicholson BD, Shinkins B, Pathiraja I, Roberts NW, James TJ, Mallett S, Perera R, Primrose JN, Mant D. Blood CEA levels for detecting recurrent colorectal cancer. Cochrane Database Syst Rev. 2015 Dec 10;12.

Shine B, McKnight RF, Leaver L, Geddes JR. Long-term effects of lithium on renal, thyroid, and parathyroid function: a retrospective analysis of laboratory data. Lancet. 2015 Aug 1;386(9992):461-8.

Holt RI, Böhning W, Guha N, Bartlett C, Cowan DA, Giraud S, Bassett EE, Sönksen PH, Böhning D. The development of decision limits for the GH-2000 detection methodology using additional insulin-like growth factor-I and amino-terminal pro-peptide of type III collagen assays. Drug Test Anal. 2015 Sep;7(9):745-55.

Kolawole K, Herrington W, James T. Development of a UPLC Method for Metformin Quantification in Plasma (Poster) IBMS congress. Birmingham, September 2015.

Oke J, Shine B, McFadden E, Stevens R, Lasserson D, Perera R. Trends in serum creatinine testing in Oxfordshire, UK, 1993-2013: a population-based cohort study. BMJ Open. 2015 Dec 16;5(12):e009459. doi: 10.1136/bmjopen-2015-009459.


Luo X1, Xu Q, James T, Davis JJ. Redox and label-free array detection of protein markers in human serum. Anal Chem. 2014; 86 :5553-8.

Shah N, Thanabalasingham G, Owen KR, James TJ. Comparability of high-sensitivity CRP methods to detect maturity-onset diabetes of the young due to HNF1A mutations. Br J Biomed Sci. 2014; 71: 84-5.

Brian D Nicholson, Bethany Shinkins, Indika Pathiraja, Nia W Roberts,Tim J James,Susan Mallett, Rafael Perera, John N Primrose, David Mant. Blood CEA levels for detecting recurrent colorectal cancer. Protocol. Cochrane Database of Systematic Reviews. June 2014.

Shinkins B, Perera R, Nicholson B, James T, Primrose J, Mant D. CEA monitoring to detect recurrence of colorectal cancer: how should we interpret the test results? Clinical Chemistry 2014;60:1572-4.

Rehman SM, Elzain O, Mitchell J, Shine B, Bowler IC, Sayeed R, Westaby S, Ratnatunga C. Risk factors for mediastinitis following cardiac surgery: the importance of managing obesity. J Hosp Infect. 2014 Oct;88(2):96-102.

Frighi V, Morovat A, Stephenson MT, White SJ, Hammond CV, Goodwin GM. Vitamin D deficiency in patients with intellectual disabilities: prevalence, risk factors and management strategies. Br J Psychiatry. 2014 Dec;205(6):458-64.

Farmer AJ, Stevens R, Hirst J, Lung T, Oke J, Clarke P, Glasziou P, Neil A, Dunger D, M Colhoun H, Pugh C, Wong G, Perera R, Shine B. Optimal strategies for identifying kidney disease in diabetes: properties of screening tests, progression of renal dysfunction and impact of treatment - systematic review and modelling of progression and cost-effectiveness. Health Technol Assess. 2014 Feb;18(14):1-128.


Nagrebetsky A, Jin J, Stevens R, James T, Adler A, Park P, Craven A, Shine B, Farmer A. Diagnostic accuracy of urine dipstick testing in screening for microalbuminuria in type 2 diabetes: a cohort study in primary care. Family Practice. 2013;30:142-52.

Luo X, Xu M, Freeman C, James T, and Davis JJ. Ultrasensitive Label Free Electrical Detection of Insulin in Neat Blood Serum. Analytical Chemistry, 2013;85:4129-34.

Guha N. Assays for GH, IGF-I, and IGF binding protein-3. Methods Mol Biol. 2013;1065:117-28.

Patel MV, Shine BS, Watkinson P, James T. A comparison of formulae for calculating plasma osmolality in hyperosmolar hyperglycaemic state (HHS). (Poster W15) ACB National Meeting (Focus 2013).

Maunsell-Browne ZJ, Justice S, Chung K, Ferguson H, Mitchell K, Mevada C, James TJ. Iohexol Clearance: Improving Quality, Safety and Productivity for Formal Assessment of GFR. (Poster W71) ACB National Meeting (Focus 2013).

Worth C, James T, Shine B. Two year follow up audit of patients requiring CSF xanthochromia analysis. (Poster Th38) ACB National Meeting (Focus 2013).

Segal, HC, Burgess AI, Poole DL, Taj, N, James, TJ, Mehta Z, Rothwell PM. Lipoprotein associated phospholipase A2 (Lp-PLA2) and long-term prognosis after TIA and stroke. (Poster) European Stroke Conference. May 2013. London.

Morovat A, Catchpole A, Meurisse A, Carlisi A, Bekaert A, Rousselle O, Paddon M, James T, Cavalier E. IDS iSYS automated intact procollagen-1-N-terminus pro-peptide assay: Method evaluation and reference intervals in adults and children. Clin Chem Lab Med 2013; 51: 2009-18.

Rowland R, O’Hara GA, Hamilla M, Poulton I, Donaldson H, Dinsmore L, James T, Barnes E, Klenerman P, Gilbert SC, Hill A, Shine B, McShane H. Determining the validity of hospital laboratory reference intervals for healthy young adults participating in early clinical trials of candidate vaccines. Hum Vaccin Immunother. 2013; 9: 1741-51.

Shah N, Thanabalasingham G, Owen KR, James TJ. A comparison of high sensitivity CRP methods at low concentrations. (Poster) IBMS congress. Birmingham, September 2013.


Brook MO, Bottomley MJ, Mevada C, Svistunova A, Bielinska AM, James T, Kalachik A, Harden PN.
Repeat testing is essential when estimating chronic kidney disease prevalence and associated cardiovascular risk. QJM. 2012; 105: 247-255.

Watkinson PJ, Barber VS, Amira E, James T, Taylor R, Young JD. The effects of precision, haematocrit, pH and oxygen tension on point-of-care glucose measurement in critically ill patients: a prospective study. Ann Clin Biochem. 2012; 49: 144-51.

Nowak N, Szopa M, Thanabalasingham G, McDonald TJ, Colclough K, Skupien J, James TJ, Kiec-Wilk B, Kozek E, Mlynarski W, Hattersley AT, Owen KR, Malecki MT. Cystatin C is not a good candidate biomarker for HNF1A-MODY. Acta Diabetol. 2012 Feb 19. [Epub ahead of print].

Evans PD, Chung K, James TJ, Tan GD, McIntyre CW1, Dose Dependent Effect of Weight Loss on Hyperfiltration as a Result of Bariatric Surgery. British Renal Society Meeting, Manchester, May 2012.