NMDA Antibodies

Also known as: NMDAR

N-methyl-D-aspartate (NMDA) receptor antibodies are associated with the different sub units of the NMDA receptor. Antibodies to the delta or NR2 subunits of NMDA receptor are associated with limbic encephalitis, systemic lupus erythematosus (SLE), ataxia and epilepsia partialis continua. Antibodies against the NR1, NR2A and NR2B subunits of the NMDA are found in patients presenting with psychiatric symptoms, amnesia, seizures, dyskinesias, autonomic dysfunction and loss of consciousness.

Dalmau J et al. Lancet Neurol. 2008 Dec;7(12):1091-8

Specimen requirements

A paired 0.5ml serum and 0.5ml CSF sample

Cost

Fixed Cell Assay £35

Laboratory turnaround time

Fixed Cell Assay: 7 days

Laboratory method

Cell based assay

Immunofluorescence Microscopy: Fixed Cell

Reference range/units

Not applicable

Associated tests

Not applicable

Sample stability

4 months at 2-8ºC

Shipping and storage

UK and Ireland

Ambient temperature and first class post. Hays DX users please enquire via email below.

International

Ambient temperature if courier will deliver within 72 hours otherwise consider refrigerated transport. Freezing is not a requirement.

Ensure delivery Monday to Friday 09:00 - 17:30.

Further information and contact details

For further information, email immunology.office@nhs.net