Myelin Associated Glycoprotein Antibodies

Also known as: MAG; IMAG

Myelin Associated Glycoprotein (MAG) autoantibodies are frequently associated with peripheral neuropathy. These autoantibodies frequently occur with IgM paraproteinaemia. MAG autoantibodies, contribute directly to the pathogenesis of peripheral neuropathies. Patients with anti-MAG antibody titres may respond favourably to therapeutic intervention. Testing for the presence of these autoantibodies is useful for diagnosis as well as monitoring of therapy.

Specimen requirements

Serum 1ml; plasma is acceptable but CSF not required.

Cost

• UK NHS - 20 UKP
• International and Private - 30 UKP

Laboratory turnaround time

14 days

Laboratory method

ELISA

Reference range/units

• Negative = <1000 BTU (Bulhmann Titre Units)
• Low Positive = 1000-3000 BTU
• High Positive > 70000 BTU

Associated tests

Not applicable

Sample stability

30 days at 2-8ºC

Shipping and storage

UK and Ireland

Ambient temperature and first class post. Hays DX users please enquire via email below.

International

Ambient temperature if courier will deliver within 72 hours otherwise consider refrigerated transport. Freezing is not a requirement.

Ensure delivery Monday to Friday 09:00 - 17:30.

Further information and contact details

For further information, email immunology.office@nhs.net