This website uses cookies

Some cookies are essential to the running of the website, while others (analytics) help us to make improvements. We also incorporate functionality from other websites, such as video, social media feeds and ReachDeck (text-to-speech and translations services) which may set cookies. More on how we use cookies

Set cookie preferences
Oxford University Hospitals NHS Foundation Trust
Immunology Laboratory

Alert Coronavirus / COVID-19

If you have a new continuous cough, a high temperature, or a loss or change to your sense of taste or smell, do not come to our hospitals. Follow the national advice on coronavirus (COVID-19).

Please find information on our services and visiting restrictions in our COVID-19 section.

Patients and visitors must wear a face covering in our hospitals.

This site is best viewed with a modern browser. You appear to be using an old version of Internet Explorer.

Haemolytic Complement Activity - Classical and Alternative Pathways

Also known as: CH50; AP50; CH100; AP100

Test of integrity of classical and alternate lytic pathways of complement. Such conditions are rare and present either with a predisposition to recurrent bacterial infections, especially meningococcal (C5-9, properdin) and pneumococcal infection (C1-4), or with increased susceptibility to immune complex diseases such as SLE (C1-4).

NB If you suspect this condition, we suggest that you discuss this with an Immunologist prior to requesting this assay.

Specimen requirements

Serum - 1ml

Cost

Price on application

Laboratory turnaround time

31 days

Laboratory method

Haemolytic

Reference range/units

Reported as Normal or a percentage of normal.

Normal is equal or >80% of the control.

Associated tests

Not applicable

Shipping and storage

Sample needs to reach the Laboratory within 8 hours of venepuncture.

Patients with any form of meningococcal disease, particularly if recurrent, should be screened in convalescence with a CH100.

Further information and contact details

For further information, email immunology.office@nhs.net