Ganglioside Antibodies

Also known as: GM1; GQ1b

Anti-ganglioside antibodies are associated with several immunologically mediated peripheral neuropathies e.g. anti-GM1 (IgM) with multifocal motor neuropathy, GQ1b (IgG) with the Miller-Fisher syndrome and GM1 (IgG) with the Guillain-Barre syndrome.

Anti-ganglioside antibodies are often found at low titres in normal individuals.

Specimen requirements

Serum 1ml; CSF not required but can be analysed

Cost

• UK NHS - 15 UKP
• International and Private - 20 UKP each for either GM1 or GQ1b

Laboratory turnaround time

21 days

Laboratory method

ELISA

Reference range/units

GM1

Negative ≤ 1/200 titre , Equivocal = 1/400, Positive ,≥ 1/800

GQ1b Negative = <1/50, Equivocal = 1/50, positive ≥ 1/100

Associated tests

Not applicable

Sample stability

2 months at 2-8ºC

Shipping and storage

UK and Ireland

Ambient temperature and first class post. Hays DX users please enquire via email below.

International

Ambient temperature if courier will deliver within 72 hours otherwise consider refrigerated transport. Freezing is not a requirement.

Ensure delivery Monday to Friday 9.00am - 5.30pm.

Further information and contact details

For further information, email immunology.office@nhs.net