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Immunology Laboratory

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Ganglionic Acetylcholine Receptor Antibodies

Also known as: Alpha3; AChR; α3AChR

Ganglionic (alpha3) acetylcholine receptor antibodies have been reported in the sera of some patients with autoimmune autonomic neuropathy. Their frequency is not yet known. They may also be found in patients with paraneoplastic disorders particularly in association with small cell lung carcinoma (SCLC) or thymoma. Their presence suggests an immunotherapy-responsive condition - Vernino S. et al., NEJM 2000:343 847-855

Specimen requirements

Serum 1ml; CSF not suitable for testing.


50 UKP - UK NHS, International and Private

Laboratory turnaround time

42 days

Laboratory method

Radioimmunoassay (RIA)

Reference range/units

Not applicable

Associated tests

Not applicable

Sample stability

4 months at 2-8ºC

Shipping and storage

UK and Ireland

Ambient temperature and first class post. Hays DX users please enquire via email below.


Ambient temperature if courier will deliver within 72 hours otherwise consider refrigerated transport. Freezing is not a requirement.

Ensure delivery Monday to Friday 09:00 - 17:30.

UKAS Accreditation status

This test is not UKAS Accredited as it is performed by the University of Oxford Neuroimmunology Research Group.

Further information and contact details

For further information, email

Last reviewed:06 October 2023