High sensitivity Myasthenia Gravis screen (Clustered ACHR antibodies/MuSK antibodies/LRP4 antibodies)

This assay is semi quantitative and is normally used by users as a third line assay to investigate patients who have shown negativity by RIA or by alternative ELISAs not offered at Oxford.

Please note: historically, this assay has been known as the 'low affinity ACHR assay': in an attempt to try and standardise nomenclature across different assays, we are renaming this assay as the High Sensitivity Myasthenia Gravis Screen.

Specimen requirements

Serum 1ml; plasma is acceptable but CSF not required

Cost

100 UKP - UK NHS, International and Private; price includes AChR, MuSK and LRP4

Laboratory turnaround time

14 days

Laboratory method

Cell based assay

Reference range/units

Not applicable

Associated tests

Not applicable

Sample stability

4 months at 2-8ºC

Shipping and storage

UK and Ireland

Ambient temperature and first class post. Hays DX users please enquire via email below.

International

Ambient temperature if courier will deliver within 72 hours otherwise consider refrigerated transport. Freezing is not a requirement.

Ensure delivery Monday to Friday 09:00 - 17:30.

UKAS Accreditation status

This test is not UKAS Accredited as it is performed by the University of Oxford Neuroimmunology Research Group.

Further information and contact details

For further information, email immunology.office@nhs.net

Last reviewed:22 May 2023

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