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Immunology Laboratory

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Acetylcholine Receptor Antibodies

Also known as: ACR; ACHR; Myasthenia antibody; Motor end plate antibody; MG antibody

Acetylcholine receptor antibodies are a highly sensitive and specific marker for generalised myasthenia gravis (80-90% sensitivity); up to 90% of generalised MG cases are ACHR positive for ACHR antibodies whilst in pure ocular MG up to 50% of patients are positive.

Specimen requirements

Serum -1ml
Plasma and CSF are not acceptable


  • UK NHS - 15 UKP
  • International and Private - 20 UKP

Laboratory turnaround time

14 days

Laboratory method

Radioimmunoassay (RIA)

Reference range/units

Negative is <5 X10-10 mole per litre

Low Positive is 5 to 10 X10-10 mole per litre

Positive is >10 X10-10 mole per litre

Associated tests

Sample stability

2 months at 2-8ÂșC

Shipping and storage

UK and Ireland

Ambient temperature and first class post. Hays DX users please enquire via email below.


Ambient temperature if courier will deliver within 72 hours otherwise consider refrigerated transport. Freezing is not a requirement.

Ensure delivery Monday to Friday 09:00 - 17:30.

Further information and contact details

For further information, email

Last reviewed:12 September 2022