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Oxford University Hospitals NHS Foundation Trust
Physiotherapy at the NOC

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Current research projects

Physiotherapy Rehabilitation for Osteoporotic Vertebral Fracture (PROVE)

Karen Barker, Muhammad K Javaid, Meredith Newman, Catherine Minns Lowe, Tamsin Hughes, Nigel Stallard, Jose Leal, Varsha Gandhi, Sallie Lamb.

Objective: to evaluate the effects of exercise and manual therapy physiotherapy treatments upon quality of life, function and pain, for people who have had one or more spinal fractures due to Osteoporosis.

For more information, see

Community based Rehabilitation after Knee Arthroplasty (CORKA)

Karen Barker, David Beard, Gary Collins, Avril Drummond, Sally Lamb, Andrew Price, Helen Campbell, Fran Toye, Martin Underwood, Susan Dutton.

Objective: to compare the patient reported functional outcome and quality of life of the CORKA rehabilitation protocol versus usual care in those at risk of a poor outcome post knee arthroplasty.

For more information, see

'WALK30X5': The development and feasibility evaluation of a physiotherapy walking programme for people with mild to moderate musculoskeletal conditions

Catherine Minns Lowe, Paul Kelly, Charlie Foster, Karen Barker.

Objective: to develop and refine an evidence-based, web-based physiotherapy walking programme intervention including podcasts, blog and links. To test the feasibility and acceptability of the intervention.

Cementless versus cemented unicompartmental knee replacement: 1-5 year post-operative outcome study

Cathy Jenkins, Hemant Pandit,Karen Barker, David Murray.

Objective: to determine the incidence of problems following cementless medial UKR and compare this with cemented medial UKR.

For more information, see

Oxford unicompartmental knee replacement: second decade outcome study

Cathy Jenkins, Hemant Pandit,Karen Barker, David Murray.

Objective: to identify, from postoperative X-rays, which patients are more at risk of developing Lateral Compartment Osteoarthritis (LCOA) in the second decade after UKR surgery.

What interventions are used to improve excercise adherence in community dwelling older people: a systematic review

Jonathan Room, Mary Boulton, Helen Dawes, Karen Barker
Faculty of Health and Life Sciences, Oxford Brookes University

Objectives: to establish what interventions are used to improve adherence to prescribed exercise for older people and determine the effectiveness of these interventions.  

Four square step test - reliability and validity in different musculoskeletal lower limb conditions

Karen Barker, Martha Moore, Jonathan Nederend.

Objective: to assess the validity and reliability of the Four Square Step Test (FSST) for patients with hip and knee osteoarthritis and its use pre and post arthroplasty.

MAPS: Measuring Alignment and Posture of the Spine

Erin Hannink, Helen Dawes, Karen Barker

Objective: to measure concurrent validity and test-retest reliability of measuring sagittal spine alignment with a postural topography method compared to the Cobb angle from a lateral X-ray of the spine.

PRU are supporting the following studies and will be recruiting in the near future


A randomised, multi-centre, non-blinded, prospective, parallel group trial of total ankle replacement (TAR) versus ankle arthrodesis in the treatment of patients with end stage ankle osteoarthritis, comparing clinical outcomes and cost-effectiveness.

Goldberg A, Rogers M, Tetlow M, Skene S.

For more information, see


The BOOST study is a randomised controlled trial (RCT) studying two different physiotherapy treatment approaches for back and leg pain or symptoms due to lumbar spinal stenosis (also called neurogenic claudication). This is a condition that affects older people and limits their ability to walk and stand which impacts on their ability to remain independent.  The study will recruit over 400 adults over 10 NHS hospitals across England.  Participants will be 65 years and over who experience symptoms due to lumbar spinal stenosis. Participants will be randomised into one of two groups:

  • TREATMENT 1: One-to-one physiotherapy treatment (1 to 3 appointments)
  • TREATMENT 2: A group physiotherapy programme (12 classes)

For more information, see