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Oxford University Hospitals NHS Foundation Trust

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Boosting the therapeutic benefits of prism adaptation by combining it with tDCS

Trial categories: Brain

Sponsoring organisation: University of Oxford

We are looking for volunteers between 18 and 85 who have suffered from a stroke or an injury to the right side of the brain. We are particularly interested in testing people who have problems in attention, vision, memory or action in the left part of space or the left side of their body (the so-called 'neglect' syndrome).

We would like to test whether transcranial direct current stimulation, a painless, non-invasive way of stimulating the brain, can improve the effectiveness of a behavioural therapy for 'neglect' called prism adaptation.

The study will involve 2 phases, each lasting 12 weeks with a 1 month break in between. Each phase will include 5 daily rehabilitation sessions. In addition, there will be several brain scans and behavioural tests in the weeks before and after the therapy. These sessions will last a few hours each, and will be spaced out over the 12 weeks. The study will take place at the John Radcliffe Hospital, Oxford.

Participants will be reimbursed for their time and travel expenses.

If you have a metallic implant, cardiac pacemaker, a history of epilepsy, are pregnant, or suffer from claustrophobia, there are parts of the study you would not be able to participate in, so please discuss this with us and we will aim to adapt the study to suit your needs.

Dr Jacinta O'Shea
Oxford Centre for Functional MRI of the Brain (FMRIB)
Department of Clinical Neurosciences
University of Oxford
John Radcliffe Hospital
Headington, Oxford OX3 9DU

If you are interested, please contact our study coordinator:

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