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Oxford University Hospitals NHS Foundation Trust
Physiotherapy at the NOC

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Current research projects

Physiotherapy Rehabilitation for Osteoporotic Vertebral Fracture (PROVE)

Karen Barker, Muhammad K Javaid, Meredith Newman, Catherine Minns Lowe, Tamsin Hughes, Nigel Stallard, Jose Leal, Varsha Gandhi, Sallie Lamb.

Objective: To evaluate the effects of exercise and manual therapy physiotherapy treatments upon quality of life, function and pain, for people who have had one or more spinal fractures due to Osteoporosis.

For more information, see

Community based Rehabilitation after Knee Arthroplasty (CORKA)

Karen Barker, David Beard, Gary Collins, Avril Drummond, Sally Lamb, Andrew Price, Helen Campbell, Fran Toye, Martin Underwood, Susan Dutton.

Objective: To compare the patient reported functional outcome and quality of life of the CORKA rehabilitation protocol versus usual care in those at risk of a poor outcome post knee arthroplasty.

For more information, see

“WALK30X5”: The development and feasibility evaluation of a physiotherapy walking programme for people with mild to moderate musculoskeletal conditions

Catherine Minns Lowe, Paul Kelly, Charlie Foster, Karen Barker.

Objective: To develop and refine an evidence-based, web-based physiotherapy walking programme intervention including podcasts, blog and links. To test the feasibility and acceptability of the intervention.

The clinical outcome of minimally invasive Phase 3 Oxford unicompartmental knee arthroplasty: a 15-year follow-up of 1000 UKAs

H. Pandit, T. W. Hamilton, C. Jenkins, S. J. Mellon, C. A. F. Dodd, D. W. Murray.

Objective: To determine the long term survival, clinical outcome and complication rate following this procedure. To do this we regularly assess patients clinically and radiologically. Assessment intervals are: pre-operatively and at regular intervals post-operatively (1, 2, 5, 7, 10, 12, 15 and 17+ years).

For more information, see

Cementless versus cemented unicompartmental knee replacement: 1-5 year post-operative outcome study

Cathy Jenkins, Hemant Pandit,Karen Barker, David Murray.

Objective: To determine the incidence of problems following cementless medial UKR and compare this with cemented medial UKR.

For more information, see

Oxford unicompartmental knee replacement: second decade outcome study

Cathy Jenkins, Hemant Pandit,Karen Barker, David Murray.

Objective: To identify, from post-operative x-rays, which patients are more at risk of developing Lateral Compartment Osteoarthritis (LCOA) in the second decade after UKR surgery.

Knee arthroplasty patients predicted versus actual recovery (KAPPA): what are their expectations about time of recovery following surgery and how long before they can do the tasks they want to do?

Cathy Jenkins, Sam Pemberton, Erin Hannink, Karen Barker.

Objective: To determine evidence based guidance for the length of time it will take to return to specific valued functional or leisure tasks in patients with osteoarthritis or Rheumatoid arthritis following KR. 

What interventions are used to improve excercise adherence in community dwelling older people: a systematic review

Jonathan Room, Mary Boulton, Helen Dawes, Karen Barker
Faculty of Health and Life Sciences, Oxford Brookes University

Objectives: To establish what interventions are used to improve adherence to prescribed exercise for older people and determine the effectiveness of these interventions.  

Exeter primary hip outcomes study (EPOS) - 15 year follow up

Linda Davies, Karen Barker

Objective: This longitudinal study was developed to gather information on patients’ quality of life which would then be compared with clinical and radiological outcomes.  This is a multi-centre collaborative study between the NHS and Stryker.  Currently there are 102 patients still involved in the study at the Oxford site.

Hip osteoarthritis optimal physiotherapy exercise study (HOOPes)

Linda Davies, Francine Toye, Karen Barker

Objective: The feasibility study aims to develop an optimal exercise package for patients with early hip osteoarthritis (OA).

3D technology enhanced patient information (TEPI) for orthopaedic operations - improving information and unmet needs of patients

Jonathan Rees, Jane Moser, Sue Ziebland, Andrew Price, Karen Barker, David Beard, David Murray, Sion Glynn Jones, Jim Davies, David Murray, Andrew Carr.

Objective: To explore patients experiences of TEPI and written information in relation to two commonly performed orthopaedic operations; Unicompartmental Knee Replacement (UKR) and Arthroscopic Sub-Acromial Surgery (ASAD) of the shoulder. Using the feedback both patient information resources will be updated prior to use in clinical practice. In addition the patient experiences of information given to patients undergoing UKR or ASAD will be included on the Health talk online web resource.

Validity and reliability of the figure of 8 walk test

Martha Moore, Karen Barker

Objective: To investigate the validity and reliability of the Figure of 8 Walk Test for participants one year after knee replacement at home and in clinical settings.

Four square step test - reliability and validity in different musculoskeletal lower limb conditions

Karen Barker, Martha Moore, Jonathan Nederend.

Objective: To assess the validity and reliability of the Four Square Step Test (FSST) for patients with hip and knee osteoarthritis and its use pre and post arthroplasty.

A study of the validity of the timed loaded standing test (TLS) in people with vertebral osteoporosis

Meredith Newman, Ion Lascurian, Varsha Gandhi, Tamsin Hughes, Dax Steins, Karan Vadher, Karen Barker

Objective: The overall aim of this study is to determine if the Timed Loaded Standing (TLS) test is a suitable assessment of back extensor muscle endurance in people with vertebral osteoporosis and OVF and back pain. 

PRU are supporting the following studies and will be recruiting in the near future:


A randomised, multi-centre, non-blinded, prospective, parallel group trial of total ankle replacement (TAR) versus ankle arthrodesis in the treatment of patients with end stage ankle osteoarthritis, comparing clinical outcomes and cost-effectiveness.

Goldberg A, Rogers M, Tetlow M, Skene S.

For more information, see


The STAR study is a randomised controlled trial (RCT) aiming to evaluate the clinical effectiveness and cost-effectiveness of the STAR care pathway for patients with long-term pain after total knee replacement for osteoarthritis. A total of 380 patients will be recruited over 4 centres beginning in September 2016 and will continue for 30 months. The treatment arm of the study includes usual care plus an assessment with a physiotherapy extended scope practitioner and 6 telephone calls over 12 months with a view of referring patients on to relevant treatments for their long-term symptoms.

For more information, see


The BOOST study is a randomised controlled trial (RCT) studying two different physiotherapy treatment approaches for back and leg pain or symptoms due to lumbar spinal stenosis (also called neurogenic claudication). This is a condition that affects older people and limits their ability to walk and stand which impacts on their ability to remain independent.  The study will recruit over 400 adults over 10 NHS hospitals across England.  Participants will be 65 years and over who experience symptoms due to lumbar spinal stenosis. Participants will be randomised into one of two groups:

  • TREATMENT 1: One-to-one physiotherapy treatment (1 to 3 appointments)
  • TREATMENT 2: A group physiotherapy programme (12 classes)

For more information, see