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Oxford University Hospitals NHS Foundation Trust
Immunology

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MuSK Antibodies

Also known as: Muscle specific tyrosine kinase

Muscle specific tyrosine kinase (MUSK) is a surface membrane enzyme that is essential in aggregating Acetylcholine receptor during the development of the neuromuscular junction. Recent studies have shown that antibodies to Musk are present in 40% to 50% of patients with generalized Acetylcholine Receptor seronegative MG. Anti-Musk antibodies have not been found in patients with purely ocular myasthenia or in those with anti-acetylcholine receptor antibodies.

Specimen requirements

Serum 1ml; plasma is acceptable but CSF not required.

Cost

  • UK NHS - 20 UKP
  • International and Private - 30 UKP

Laboratory turnaround time

21 days

Laboratory method

Radioimmunoassay (RIA)

Reference range/units

Not applicable

Associated tests

Not applicable

Shipping and storage

UK and Ireland

Ambient temperature and first class post. Hays DX users please enquire via email below.

International

Ambient temperature if courier will deliver within 72 hours otherwise consider refrigerated transport. Freezing is not a requirement.

Ensure delivery Monday to Friday 07:00 - 17:30.

Further information and contact details

For further information, email immunology.office@nhs.net