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Oxford University Hospitals NHS Foundation Trust

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Coeliac Antibodies

Also known as: Endomysial Antibodies; Endomysium Antibodies; IgA Endomysial Antibodies

IgA endomysial antibodies are currently the most specific assay for Coeliac Disease screening. NICE guidelines 2009 (sensitivity 70 - 90%, specificity 90 - 100%) and will detect virtually all cases of untreated coeliac disease except those with co-existing IgA deficiency. For this reason, a total serum IgA is performed alongside, if this is low (<0.06 g/l) and the endomysial antibody is negative, the serum is tested for IgG endomysial antibodies. There is a good correlation of endomysial antibody with disease activity, with relapse or poor compliance with a gluten free diet often associated with a return to antibody positivity. IgA endomysial antibodies are also present in patients with Dermatitis Herpetiformis (DH).

See CG86 for further information on the NICE Guidelines:

Specimen requirements

Serum or plasma - 1ml


Price on application

Laboratory turnaround time

7 days

Laboratory method


Reference range/units

Reported as Positive or Negative

Associated tests

  • TTG antibody
  • IgG endomysial antibodies

Shipping and storage

UK and Ireland

Ambient temperature and first class post. Hays DX users please enquire via email below.


Ambient temperature if courier will deliver within 72 hours otherwise consider refrigerated transport. Freezing is not a requirement.

Ensure delivery Monday to Friday 07:00 - 17:30.

Further information and contact details

For further information, email