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Oxford University Hospitals NHS Foundation Trust

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Determining the role of GABA in eye dominance and visual suppression

Trial categories: Brain; Eyes

Sponsoring organisation: University of Oxford

Brain responses during human amblyopia

We are looking for participants aged 18-45 who have/have had a lazy eye, or have received patching therapy, or have been diagnosed with amblyopia.

We are studying the brain responses of amblyopic participants using non-invasive magnetic resonance imaging.

Prospective participants would take part in three sessions:

  • the first 1h session will be with an orthoptist at the Oxford Eye Hospital;
  • the second session will be a 1h test on various computerised visual tasks at the Department of Physiology, Anatomy and Genetics, and
  • the third session will be a 1.45 h brain scan at the Oxford Centre for Functional Imaging of the Brain (FMRIB).

Participants will be reimbursed for their time.

Summary

Combining the information from our two eyes allows us to experience the world in depth, in addition to expanding the area of the world that we can see. Some people who experience monocular deprivation when they are children, due to a 'lazy eye', or very different visual corrections between left and right eyes, are later unable to see in depth.

In addition to people who are unable to see in depth, there are some people who have one eye that is much more dominant than the other, and they favour this eye.

Participants will be reimbursed for their time and travel expenses.

If you are interested and would like more information, please contact our study researcher:

Dr Betina Ip

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