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Oxford University Hospitals NHS Foundation Trust

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About the conditions

Osteogenesis Imperfecta, Fibrous Dysplasia and X-Linked Hypophosphataemia are three rare conditions which affect the bones.

People with Osteogenesis Imperfecta have a genetic mutation that alters the body's production of collagen which affects the bones and other tissues.

People with Fibrous Dysplasia are also more likely to suffer fractures as they have areas of weaker fibrous tissue instead of normal bone.

People with X-Linked Hypophosphataemia may have skeletal abnormalities, kidney stones and dental abscesses.

Although the three conditions are different, they are being studied together because they have much in common, including symptoms such as bone pain.

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